Michael Jackson's Ghost Spooks Propofol Maker Teva

willddoMJwillddoMJ Posts: 699
edited January 1970 in News
Michael Jackson's Ghost Spooks Propofol Maker Teva

The worldwide scorn directed at those closest to Michael Jackson in his final days may have extended to the drug Propofol and its Irvine-based maker, which announced it is laying off 200 employees this year after having already let go 70 workers.

Teva Pharmaceuticals maintains it already discontinued the hypnotic drug--not because of Jackson's death, but because Propofol was hard to manufacture, the company got little or no profit from it and there were pending lawsuits tied to it.


​Risks from the nonmedical use of Propofol were greatly exposed when the Los Angeles County coroner concluded in August 2009 that the King of Pop died from a mixture of Propofol--nicknamed "Milk of Amnesia"--and the benzodiazepine drug Lorazepam. Ten bottles of Propofol were found in Jackson's home.

Propofol and Teva, which is headquartered in Israel, have had a rocky relationship. The company previously halted production and recalled some Propofol in 2009 after 41 patients fell ill with flu-like symptoms. That fueled several of the lawsuits.

Teva announced it will kill 195 of its Irvine jobs by Feb. 6, according to an Orange County Register report.

"Our Irvine, California, facility has been under a voluntary manufacturing and distribution hold since April 2010," said Denise Bradley, Teva spokeswoman in a company statement. "Prior to this reduction, we have not laid off any employees as a result of this voluntary production hold. The jobs that are being eliminated are all various production jobs and support staff at the facility."'

They should moonwalk out to their cars.


http://blogs.ocweekly.com/navelgazing/2011/01/michael_jackson_propofol_teva.php

Comments

  • SinderellaSinderella Posts: 1,334
    Interesting!!

    Definitley worth looking into more.
    I recall Fleak at the prelim saying she -at the time in 09- had no idea what propofol was,and tbh I don't think the rest of the world did either.There have only been a handful of deaths related back to an overdose/misusage of this drug,if that..I think it is about 2/3 people and that was down to self injecting and one case was due to intoxication from 100+injections of the liquid.
    There is little to nothing really known about propofol before this happened.I had never heard of it and had to google the effects when Michael 'died' from it so I wonder what these numerous 'pending law suits' are against the company.
    I can see several where from people getting the flu or something from it but other than that...what other law suits could be tied to it?
  • MissGMissG Posts: 7,403
    Michael Jackson's Ghost Spooks Propofol Maker Teva

    The worldwide scorn directed at those closest to Michael Jackson in his final days may have extended to the drug Propofol and its Irvine-based maker, which announced it is laying off 200 employees this year after having already let go 70 workers.

    Teva Pharmaceuticals maintains it already discontinued the hypnotic drug--not because of Jackson's death, but because Propofol was hard to manufacture, the company got little or no profit from it and there were pending lawsuits tied to it.


    ​Risks from the nonmedical use of Propofol were greatly exposed when the Los Angeles County coroner concluded in August 2009 that the King of Pop died from a mixture of Propofol--nicknamed "Milk of Amnesia"--and the benzodiazepine drug Lorazepam. Ten bottles of Propofol were found in Jackson's home.

    Propofol and Teva, which is headquartered in Israel, have had a rocky relationship. The company previously halted production and recalled some Propofol in 2009 after 41 patients fell ill with flu-like symptoms. That fueled several of the lawsuits.

    Teva announced it will kill 195 of its Irvine jobs by Feb. 6, according to an Orange County Register report.

    "Our Irvine, California, facility has been under a voluntary manufacturing and distribution hold since April 2010," said Denise Bradley, Teva spokeswoman in a company statement. "Prior to this reduction, we have not laid off any employees as a result of this voluntary production hold. The jobs that are being eliminated are all various production jobs and support staff at the facility."'

    They should moonwalk out to their cars.



    http://blogs.ocweekly.com/navelgazing/2011/01/michael_jackson_propofol_teva.php
    Don´t know if can be useful. Here it goes.
    Heart Attack Victim Moved for Michael Jackson
    <!-- m -->http://abcnews.go.com/GMA/MichaelJackso ... ?id=529513<!-- m -->
    (Page Unavailable <!-- s:roll: -->:roll:<!-- s:roll: --> )
    Feb. 25, 2005
    A woman who had suffered a massive heart attack died after hospital personnel moved her out of a trauma room to accommodate a flu-stricken Michael Jackson, the patient's family said.

    Jury selection in Jackson's child molestation child had to be temporarily postponed Feb. 15 when the pop star was taken to Marian Medical Center in Santa Maria, Calif., complaining of flu-like symptoms. Manuela Gomez Ruiz, a 74-year-old grandmother, was moved from the primary trauma room and taken off the machine ventilator, with her breathing instead assisted manually by hand pump, until she was relocated to a smaller room nearby, her family told ABC News.
    <!-- m -->http://forums.cnet.com/7723-6130_102-88624.html<!-- m -->
  • nefarinefari Posts: 1,227
    I had Propofol numerous times before 2009 and the one thing that stands out to me is every time I am laying on the table waiting on them to hook me up, I get asked over and over about old injuries that could start to bleed out. They stress to me that Propofol can cause old injuries to bleed and it seems to be a big concern. This always made me a bit nervous even though I've been under at least 6 times with Propofol.
  • nefari
    what kind of operationa did you have that you had to take this drug propofol?
    i never heard of it untill this thing with michael .
    hugs
    mjfjei7777
  • SinderellaSinderella Posts: 1,334
    Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

    She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.
  • GraceGrace Posts: 2,864
    I'm adding a post from another thread.
    Mid July 2009 the first recalls of Propofol were published by the FDA for safety reasons (bacterial contamination of the product). The timing is not astonishing - the name of Propofol was in all newspapers after Michael's "passing". However:
    A Teva spokeswoman said the company had been contacted by the Drug Enforcement Administration about a lot number on a specific propofol vial "in relation to an investigation they are conducting," which she did not confirm or deny involved the Jackson death.

    That lot number, she said, is not one of those involved in the recall.
    http://www.medpagetoday.com/ProductAlert/Prescriptions/15134
    More than 57,000 vials of Teva-manufactured propofol were recalled after the U.S. Centers for Disease Control and Prevention (CDC) issued a health advisory on July 13, 2009, warning physicians not to use 100 ml vials of propofol from two lots.

    One of main manufacturers of Propofol is TEVA, another is Hospira.
    Teva received a warning from FDA in April 2010 after they had to recall 100 ml vials from the market:
    Teva Pharmaceuticals failed to have proper quality control measures in place to prevent bacterial contamination from entering batches of their generic version of the anesthetic propofol, leading to a recall last year after at least 40 people became ill, according to federal inspectors.
    http://www.aboutlawsuits.com/teva-propofol-warning-letter-9927/

    Teva stopped production thus resulting in a product shortage in the U.S.
    The Teva propofol recall, and another propofol recall by Hospira, Inc. due to particulate matter contamination in November, has caused a shortage of propofol in the United States. As a result, the FDA has given APP Pharmaceuticals Inc. permission to import Propoven, a similar drug, into the U.S. Propoven has not been approved by FDA, but is in use in a number of other countries around the world.
    http://www.aboutlawsuits.com/teva-propofol-warning-letter-9927/

    Where do the contaminations result from?
    The drug is available as an aqueous lipid emulsion
    (Dipdvan| ICI Pharmaceuticals)
    containing I% propofol, 10% soyabean oil, 1.2% egg
    phosphatide and 2.25% glycerol.
    Product information provided with propofol states that
    the preparation should be "... drawn aseptically into a
    sterile syringe ... immediately alter opening the ampoule"
    and that it should be injected "... without delay." Despite
    these recommendations, it is often difficult in clinical
    practice to ensure that there is no delay between drawing-
    up and administration. Therefore propofol can often be
    left standing in a sterile syring~ for some period of time
    prior to administration.
    http://www.springerlink.com/content/k60121887j07mr03/
    The intravenous anaesthetic propofol may become contaminated once the ampoules have been opened. [...] When propofol is stored in opened ampoules, the bacterial contamination rate is high.
    http://www.ingentaconnect.com/content/gmed/eja/2002/00000019/00000006/art00010
    Propofol can support rapid microbial growth and endotoxin production. To avoid infectious complications, scrupulous aseptic technique should be used when preparing or administering this anesthetic.
    http://www.jstor.org/pss/30145228

    FDA issued a warning about proper handling in 2007 already.
    http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm125817.htm
    Escherichia coli is one of the most frequent causes of many common bacterial infections, including cholecystitis, bacteremia, cholangitis, urinary tract infection (UTI), and traveler's diarrhea, and other clinical infections such as neonatal meningitis and pneumonia.

    Drawing out a case that has not yet been subject to interest:
    We face three sources of contamination of the product with bacteria:
    1) the fact that the product is containing soy bean oil which as a lipid supports bacteria growth
    2) improper manufacturing
    3) improper handling at anesthesia administration in divergence to guidelines

    Therefore propofol can often be
    left standing in a sterile syring~ for some period of time
    prior to administration. For some anaesthetists, this delay
    is on occassion deliberate with several induction doses
    prepared in advance for an operating list. The problem
    of clinical practicalities occasionally resulting in diver-
    gence from package insert guidelines has been previously
    identified, l but not quantified.
    http://www.springerlink.com/content/k60121887j07mr03/
    http://michaeljacksonhoaxforum.com/phpbb2/viewtopic.php?f=217&t=17015&p=292529#p292529
    Hospira Issues Second Drug Recall in 6 Months on FDA Warning
    -Bloomberg
    04/16/2010 - Hospira Inc. recalled two drugs for the second time in six months because of manufacturing defects that prompted an April 12 warning letter from the U.S. Food and Drug Administration, said Dan Rosenberg, a company spokesman. The drugs -- Propofol, an anesthetic agent, and Liposyn, an intravenous nutritional product -- were recalled on April 1, Rosenberg said. The company told the FDA the products had been contaminated by particulates during the manufacturing process, he said. The drugs are sold to hospitals and doctors. More>>>


    Teva Pharmaceuticals USA issues a voluntary nationwide recall of Propofol Injectable Emulsion

    -FDA
    12/17/2009 - In July of 2009 Teva Pharmaceuticals USA initiated a voluntary recall of Propofol Injectable Emulsion 10 mg/mL 100 mL vials, lot numbers 31305429B and 31305430B. The product lots identified are being recalled due to the presence of elevated endotoxin levels in some vials within these lot numbers. More>>>

    Hospira Brand Propofol and Liposyn Products - Recall
    -FDA
    11/11/2009 - Hospira, Inc.and FDA notified healthcare professionals of the recall of 85 lots of Liposyn II 10%, Liposyn II 20%, Liposyn III 10%, Liposyn III 20%, and Liposyn III 30%, and 73 lots of Propofol Injectable Emulsion 1% products that begin with the lot numbers 79 and 80 because some of the containers may contain particulate matter. The source of the particulate matter has been identified as stainless steel equipment used in the manufacturing process. More>>>

    Hospira Issues Nationwide Voluntary Recall of Certain Lots of Liposyn and Propofol Products That May Contain Particulate Matter
    -Pharmaceutical Processing
    11/12/2009 - Hospira, Inc., a global specialty pharmaceutical and medication delivery company, is voluntarily recalling 85 lots of Liposyn™ II 10%, Liposyn II 20%, Liposyn III 10%, Liposyn III 20%, Liposyn III 30% and 73 lots of Propofol Injectable Emulsion 1% products that begin with the lot numbers 79 and 80 because some of the containers may contain particulate matter. More>>>

    If you or a loved one have suffered injury or loss as a result of contaminated Propofol or Liposyn you may be entitled to compensation. Contact The Propofol Lawyers of Ennis & Ennis, P.A. today for a free case evaluation by filling out the form on this page or calling toll-free 1-800-856-6405.
    http://www.ennislaw.com/propofol_liposyn_recall_news_archive.html
  • SouzaSouza Posts: 9,400
    Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

    She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

    That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

    "For we wrestle not against flesh and blood, but against principalities, against powers, against the rulers of the darkness of this world, against spiritual wickedness in high places."

  • SinderellaSinderella Posts: 1,334
    Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

    She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

    That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

    Well she is a non believer,she might have been lying to prove the whole Michael died at the hands of Murray BS,i'm just trying to find the note on fb now.LIKELY.
    I'm allergic to anaesthetic and have to be strapped down because I fit/fight the surgeons and take my socks and heart monitor's off and all kinds haha!I end up in a room on my own.
    I might ask for prop fool for this knee surgery I have to have soon and report back on my reactions,i'll tell them it's all the rage in Holland
  • SouzaSouza Posts: 9,400
    Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

    She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

    That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

    Well she is a non believer,she might have been lying to prove the whole Michael died at the hands of Murray BS,i'm just trying to find the note on fb now.LIKELY.
    I'm allergic to anaesthetic and have to be strapped down because I fit/fight the surgeons and take my socks and heart monitor's off and all kinds haha!I end up in a room on my own.
    I might ask for prop fool for this knee surgery I have to have soon and report back on my reactions,i'll tell them it's all the rage in Holland

    The room with those big cushions attached to the walls you mean? <!-- s:lol: -->:lol:<!-- s:lol: -->

    "For we wrestle not against flesh and blood, but against principalities, against powers, against the rulers of the darkness of this world, against spiritual wickedness in high places."

  • SinderellaSinderella Posts: 1,334
    Hell yeah!Don't be fooled,they are really comfy and if you have a pack of sharpies,you can decorate it how you want
  • Someone on my facebook list-a non believer did a note thing about her operation and her whole drama in hospital(I have no idea why but she did lol)and she said she got given propofol for her op.She slipped on some ice and broke her wrist and the op was to straighten it out so it didn't heal weird.

    She also said something about feeling really drowsy when coming round from it and there was no way she could have done anything let alone inject herself with more.

    That's strange. I have been put down with propofol once for my knee surgery and I was gone in 2 seconds and awake even faster. Not sleepy and not drowsy at all. It was like I had never been away and I wanted to get out of bed and eat.

    Yea Souza, I think there are a couple of ways they give it and one of them the patient gets a shot of something else first (don't know what that is) and then Propofol will maintain the anesthesia. The other is straight dosing,(which my son had to maintain his coma longer to heal his brain, and yep, soon as it came off after days on it he was wide awake in what seemed like seconds.
  • SinderellaSinderella Posts: 1,334
    If I can find where she wrote it I will post it up here.

    Non's.....pfftt...what can you do..
  • MJonmindMJonmind Posts: 7,290
    Yea Souza, I think there are a couple of ways they give it and one of them the patient gets a shot of something else first (don't know what that is) and then Propofol will maintain the anesthesia. The other is straight dosing,(which my son had to maintain his coma longer to heal his brain, and yep, soon as it came off after days on it he was wide awake in what seemed like seconds.
    I'm sad to hear your son had to go through an ordeal. How's he doing now?
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